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First things first: Where did all this Real American sentiment come from? Was it something that was always a part of you, or was it dredged up by your pairing with Zeb Colter? I was off television for five months, so I had a lot of time for soul-searching, you could say. I was beyond frustrated. At first, I tried to go back to my roots in amateur wrestling. Along the way, I realized that it?s not me that?s the problem. I realized that it had to be something larger at play keeping me from the success I deserve. Then I found Zeb. Together we found Jack Swagger?s America.
What are Colter?s strongest qualities? What do you think are the things about him that are taking you to the next level? Zeb Colter is certainly a man of great conviction and passion. He has so much conviction and passion for the things that he says and the things that he actually believes in?and those are the types of things people really take hold of. They make people believers. And, of course, Zeb has decades upon decades of experience, which Jack Swagger directly benefits from: the knowledge and the tutelage. Honestly, that kind of experience translates through me, and it gives me that extra little oomph that I need in order to get over the hill to the top of the mountain.
Let?s talk about the World Heavyweight Title. If 2013 sees you recapture the gold, what will you do to make sure your title run makes more of an impact than your previous one? Winning the championship the second time in any sport, whether it?s wrestling, football, basketball or baseball is definitely harder. Once you get there, staying there, and staying relevant and being able to make an impact, is tough. I worked very hard last time, but maybe I wasn?t working smart.
That?s surprising. It would seem like the opposite is true?that your first experience would make it easier the second time around, no? I truly believe that it is harder to win the second one because you already have that target on your back, and people are looking for you a little bit more. But then, once you get there, the experience can help. Getting back is the big challenge.
How are you more of a ?Real American? than Hulk Hogan? I think I?m more of a real American than Hulk Hogan because he was doing what he did for the Hulkamaniacs. Not everyone is a Hulkamaniac. I?m doing this for all of America. I?m putting the country on my broad shoulders and carrying them to the promised land. America needs a Real American now more than ever.
To read more from this exclusive interview, pick up the June Body Issue of WWE Magazine today or SUBSCRIBE HERE?and save 70 percent off the newsstand sale price.
MOUNTAIN VIEW, Calif., May 23, 2013 /PRNewswire/ ? ;Fenwick & West LLP, one of the nation?s premier law firms providing comprehensive legal services to high technology and life science clients, today announced the results of its First Quarter 2013 Silicon Valley Venture Capital Survey.
The survey analyzed the valuations and terms of venture financings for 118 technology and life science companies headquartered in the Silicon Valley that raised capital in the first quarter of 2013.
?During the first quarter of 2013, up rounds exceeded down rounds 68% to 11%, with 21% flat. ; This was a slight decline from the fourth quarter of 2012, when up rounds exceeded down rounds 71% to 8%, with 21% flat,? said Barry Kramer, partner in the Corporate Group of Fenwick & West and co-author of the survey.
An up round is one in which the price per share at which a company sells its stock has increased since its prior financing round. Conversely, a down round is one in which the price per share has declined since a company?s prior financing round.
However, the Fenwick & West Venture Capital Barometer? ? which measures the percentage change in share price of companies funded during the quarter compared with the share price of their previous financing round ? showed a 57% average price increase for the quarter, a noticeable decline from the 85% reported in the fourth quarter of 2012. ; Similarly, the median price increase of those financings was only 14%, a significant decrease from the 41% recorded in the fourth quarter. ;
?The Barometer results showed some valuation softening this quarter,? said Kramer. ; ?We will need to see next quarter if this is an anomaly or a trend.? ;
?The best performing industries in the quarter from a valuation perspective were internet/digital media and software, but hardware and cleantech did reasonably well, with only life science performing poorly,? added Michael Patrick, partner in the Corporate Group of Fenwick & West and co-author of the survey. ;
?At the big picture level, it was a tough quarter for the venture environment, with venture investing, acquisitions and IPOs all down compared to the last quarter of 2012. ; And while valuations were reasonably healthy this quarter, they declined from last quarter. ; But with the macro environment appearing to stabilize, and Nasdaq up both in the first quarter and second quarter to date, there is reason to believe that the venture environment will improve,? added Patrick.
Complete results of the survey with related discussion are posted on Fenwick & West?s website at www.fenwick.com/vcsurvey.
About the Survey The Fenwick & West Quarterly Venture Capital Survey, co-authored by law firm partners Barry J. Kramer and Michael J. Patrick, has been published for over 10 years and offers a unique view of the venture capital market in Silicon Valley by providing insight into the changes in venture capital valuations and terms. Focusing exclusively on trends in venture financing and valuations, the Fenwick & West Survey complements the economic data presented in the Dow Jones VentureSource Survey and the MoneyTree? Report by PricewaterhouseCoopers and the National Venture Capital Association based on data from Thomson Reuters.
About Fenwick & West Established in 1972, Fenwick & West LLP is one of the nation?s premier law firms with extensive expertise in venture capital, public offerings and other corporate finance, joint ventures, M&A and strategic relationships, intellectual property, litigation and dispute resolution, taxation, antitrust and employment and labor law.
Contacts: Barry Kramer Fenwick & West LLP Phone: 650.335.7278 Email: bkramer@fenwick.com
Michael Patrick Fenwick & West LLP Phone: 650.335.7273 Email: mpatrick@fenwick.com
Merredith Branscombe Le@p! Public Relations Phone: 720.235.7363 Email: merredith@leappr.com
The bookend to Yahoo's Big News Day -- a major refresh of its photo sharing site Flickr -- will see the company drop is Flickr Pro pricing tiers as part of a bid to compete better with Facebook/Instagram and the rest of the crowded market in the online photo space. But it is not getting rid of paid tiers altogether: it's keeping an ad-free tier, called Ad Free, as well as a tier for power users, doublr, respectively priced at $49.99 and $499.99 for a year of use.
International Communication Association to hold Annual Conference in London, UKPublic release date: 20-May-2013 [ | E-mail | Share ]
Contact: John Paul Gutierrez jpgutierrez@icahdq.org International Communication Association
Explores the challenges in research for communication and the media
Washington, DC (May 20, 2013) The International Communication Association (ICA) will hold its annual conference June 17-21 in London, United Kingdom. The theme of the 2013 conference is Challenging Communication Research, challenging the status quo of past research and urging the research community to look deeper into public discourse and challenge the economic, political and technological interests in society.
Featuring over 2,100 academic papers on Communication and attended by over 2,500 Communication scholars across the globe, the ICA conference is the largest scholarly international communication conference in the world. This year's conference features a session with Colette Bowe, chair of Office of Communications (Ofcom) in the UK. Bowe along with Sascha Meinrath of the New America Foundation will discuss the pace of evolution of media and communication technology, and how its uses outrun that of legislation and regulatory mechanisms.
Chairman of Semetric and advisor of the UK Technology Strategy Board, Jeremy Silver, will deliver an address on digital media, innovation and growth in the creative business. And top communication researchers will break down "Hackgate" and the Levenson Inquiry in the session Exploring Global Implications of the UK Journalism Debacle.
ICA, with the help of the Oxford Internet Institute, London School of Economics, University of London, Frontline Club, City University of London and the University of Westminster will also host a number of preconference sessions. The variety reaches from China and the New Internet World to neuroscience with Communication Science: Evolution, Biology, and Brains.
"The drastic transformations in the ways we communicate create both perils and opportunities, all the more in a context of crisis. The pace of change constitutes a major challenge to scholars, regulators and all those involved in trying to assess the change and anticipate the future trends in further changes to come. The London conference of ICA will gather the largest concentration ever of communication scholars from around the world whose cutting-edge research represents the core of scholarly efforts in studying contemporary communication from a wide range of angles," said Francois Heinderyckx, ICA President-Elect and Professor at the Universit libre de Bruxelles.
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A complete conference guide can be found here: http://www.icahdq.org/conf/2013/Program_withDAG.pdf
Members of the media can contact jpgutierrez@icahdq.org if they wish to cover the event.
About ICA
The International Communication Association is an academic association for scholars interested in the study, teaching, and application of all aspects of human and mediated communication. With more than 4,300 members in 80 countries, ICA includes 26 Divisions and Interest Groups and publishes the Communication Yearbook and five major, peer-reviewed journals: Journal of Communication; Communication Theory; Human Communication Research; Communication, Culture & Critique; and Journal of Computer-Mediated Communication. For more information, visit http://www.icahdq.org.
[ | E-mail | Share ]
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
International Communication Association to hold Annual Conference in London, UKPublic release date: 20-May-2013 [ | E-mail | Share ]
Contact: John Paul Gutierrez jpgutierrez@icahdq.org International Communication Association
Explores the challenges in research for communication and the media
Washington, DC (May 20, 2013) The International Communication Association (ICA) will hold its annual conference June 17-21 in London, United Kingdom. The theme of the 2013 conference is Challenging Communication Research, challenging the status quo of past research and urging the research community to look deeper into public discourse and challenge the economic, political and technological interests in society.
Featuring over 2,100 academic papers on Communication and attended by over 2,500 Communication scholars across the globe, the ICA conference is the largest scholarly international communication conference in the world. This year's conference features a session with Colette Bowe, chair of Office of Communications (Ofcom) in the UK. Bowe along with Sascha Meinrath of the New America Foundation will discuss the pace of evolution of media and communication technology, and how its uses outrun that of legislation and regulatory mechanisms.
Chairman of Semetric and advisor of the UK Technology Strategy Board, Jeremy Silver, will deliver an address on digital media, innovation and growth in the creative business. And top communication researchers will break down "Hackgate" and the Levenson Inquiry in the session Exploring Global Implications of the UK Journalism Debacle.
ICA, with the help of the Oxford Internet Institute, London School of Economics, University of London, Frontline Club, City University of London and the University of Westminster will also host a number of preconference sessions. The variety reaches from China and the New Internet World to neuroscience with Communication Science: Evolution, Biology, and Brains.
"The drastic transformations in the ways we communicate create both perils and opportunities, all the more in a context of crisis. The pace of change constitutes a major challenge to scholars, regulators and all those involved in trying to assess the change and anticipate the future trends in further changes to come. The London conference of ICA will gather the largest concentration ever of communication scholars from around the world whose cutting-edge research represents the core of scholarly efforts in studying contemporary communication from a wide range of angles," said Francois Heinderyckx, ICA President-Elect and Professor at the Universit libre de Bruxelles.
###
A complete conference guide can be found here: http://www.icahdq.org/conf/2013/Program_withDAG.pdf
Members of the media can contact jpgutierrez@icahdq.org if they wish to cover the event.
About ICA
The International Communication Association is an academic association for scholars interested in the study, teaching, and application of all aspects of human and mediated communication. With more than 4,300 members in 80 countries, ICA includes 26 Divisions and Interest Groups and publishes the Communication Yearbook and five major, peer-reviewed journals: Journal of Communication; Communication Theory; Human Communication Research; Communication, Culture & Critique; and Journal of Computer-Mediated Communication. For more information, visit http://www.icahdq.org.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Google announced a number of new partner apps today on stage at Google I/O during the "Developing for Glass" session. Facebook and Twitter were the highlights of the list, which also included Evernote, Tumblr, Elle and CNN, in addition to the previously announced NYT and Path apps.
Want to control the fat in your body? And do not like your body weight to increase? If you have decided to go on a diet, do not just focus on solid food, but also some drinks such as soda, fruit juices and alcohol that are rich in calories. Here are some drinks that can help you lose weight, as reported by Livestrong.
1. Water Water is one of the best drinks that can help you lose body fat. Not only that, water also helps clean the toxins out of your body and increase your metabolism. You should drink at least six to eight glasses a day to sweep the excess fat in the body.
2. Green tea Green tea offers a wide variety of chemicals and compounds that can help you fight the fat body. Caffeine is one of the main ingredients in green tea, there are also EGCG and catechins ? a fat-burning compounds contained in green tea. A study published in the Journal of Nutrition found that consumption of green tea combined with regular exercise can help stimulate the loss of body fat, especially around the midsection.
3. Milk Milk is very helpful in removing excess fat in the body. Milk contains a lot of calcium which keeps bones strong. This drink is also useful for those who like to exercise and maintain a healthy diet. Milk is a good source of protein, which gives a lot of energy to the body and the body burns calories. Protein also helps you feel full longer. Make sure that you drink skim milk that is low in calories.
4. Tomato juice Tomato juice is a low-calorie beverage rich in anti-oxidants and fiber. This drink makes you feel full longer. You can also drink it at breakfast. Avoid too often buying bottled tomato juice because it contains high sodium.
Those are four types of drinks that can help reduce body weight. Good luck!
I?ve had many people ask me what I do for a living, and it?s quite difficult to explain. You see, I work from the ?comforts of home? and deal more with words and emails over the Web rather than face-to-face (with people). From an outsider?s point of view, that sounds like a sweet deal. You don?t have to face clients, your boss, your managers or your recruits (sounds like freelancing, doesn?t it?).
(Image Source: lnfectedxangelic)
Everyone asks me if I know of more jobs like this. In my head, I?d say, "No, thank goodness there isn?t any." Before you click away, trust me when I say this is not your typical tips to work from home type of write-up. In fact, it?s more of a horror story, less goth, more blood. When you have been in my position long enough (which in fact isn?t very long by Web standards), you realize the weirder sides of things from working online as a web editor ? things like:
Recommended Reading: Useful Tips And Guidelines To Freelance Writing
Time flies
You know how it is when parents get together and say, "oh how time flies", your kids are now in college and retirement is the next stage in life? This is different. On the Internet, time moves a lot quicker. Unlike the regular 9-to-5, unless you set your own routine, you blink once it?s Wednesday, blink twice and it?s Sunday. Ironically, the opposite is the same, spend a year on the Web and it feels like it?s been four.
(Image Source: janussyndicate)
Information covered two days ago is considered ?old?, and there is a perpetual need to always be on top of a new trend, news story or product release. In the same period it takes for you to mail a letter by post, you?d probably have gone through 6 different revolutions, uprising or scandals online. The Internet runs on a different time scale and whenever you get off the Web and check the calendar, sometimes you get a shock of how far into the year you?ve been.
What to Expect/Do
Have a routine. Always run reality checks by leaving the house, going for a run, catching up with friends or reading the newspaper (the kind that doesn?t update itself, and you can lend to someone else without fearing they?d run off with it).
Everyone hates you
This is true. If you?ve been on the Web long enough, you?d notice that hatred is the most widespread emotion you will come across. Apparently for most keyboard warriors, there are plenty of things to hate, an artist who turns up late for a concert, open letters that usually fight for a cause, even small erors (see that?) on blogposts get strongly worded emails.
(Image Source: BenHeine)
There isn?t really a reason behind it, some people just like to hate. It?s a perversion of the quote by Oscar Wilde,
"Man is least himself when he talks in his own person. Give him a mask, and he will tell you the truth."
Today?s man (and woman) is also full of unbridled hatred and a passion to be in someone?s face, virtually. Everyone has an opinion they would ?virtually die for?, and there?s nothing you can do to change their opinion, even if they want to change yours.
What to Expect/Do
Be prepared to take criticism even when you are not asking for any. If you cannot take criticism from people on the Internet, then you are better off working outside of it. Honestly, it?s not worth it. You can?t be angry all the time.
You Are Your Own Manager
If freedom is the reason you want to work from home, then the first few months will be very rough for you. There is no such thing as freedom ? what there is, is self-control, discipline and a lot of sacrifices.
You will notice a need for all this when you hear yourself give your reasons (or excuses) to clients or your boss when things are not getting done: I was distracted; The deadline is still a week off, I didn?t know the client wanted an early draft; I have to help with my daughter?s recital costume etc.
If you hated your strict supervisor in your last job, well you are going to miss the rigid atmosphere that he or she set up to allow you to work and achieve your goals. That kind of setting was optimized so you can focus on the task at hand.
Recommended Reading: 10 Tips To Make ?Working From Home? Work For You
No distractions, no calls from home, no interruptions inside that 9-to-5 zone. Your hands are tied but you get work done. And at the end of the day that is what clients and bosses look for: accomplishments.
What to Expect/Do
Be disciplined, deliver the goods, or go back the environment that allows you to do both. When will you know? When nothing gets done.
Scammers are everywhere
When receiving guest contributions (a lot of you are amazing writers by the way), I?ve come across a relatively small group of people who would do anything and everything to get a post on the site, anything except give good, original content.
Make A Stand
As an editor, it is very important to appreciate the effort your writers put into their writing. It is also equally important to demand it. Having worked with so many talented, hardworking people, I have little to no respect for writers who copy content from one site and try to pass it off as their own on another site.
As writers, we should show professional courtesy to a fellow member of the same trade, e.g. credit the person who came up with the original idea, give them a backlink to the site, mention them by name sometimes. Creativity is rare enough as it is, let?s try to not kill it off before we all stop writing altogether.
But perhaps they have their reason to resort to these actions: maybe they cannot come up with original content, maybe they think that rewording is acceptable (to them) or maybe they are literally practicing the "imitation is the best form of flattery? bit.
Go With Your Gut
Regardless of the reason, the bad thing about this is they will go with it until you catch them in the act. Sometimes you do, sometimes you don?t. But the repercussions exist ? and they hurt your reputation and your brand more than it does themselves.
Working from behind a computer screen, it?s hard to look for clues. In real life, you can study body languages, notice the pitches, stammers, and a-second-too-long replies, but not when all you have is text. So what is there for an editor to do? Roll with the punches and pray that that gut instinct of yours kicks in when it needs to.
What to Expect/Do
Be very careful(?). (I have no idea actually. I usually wait for my guts and/or short fuse to tell me what to do. Maybe you have a better idea).
It?s the People
For what it?s worth, working on the Web is really fun. You get to meet and communicate with a lot of enthusiastic people who are doing great things with their lives. No where else can you find an environment where there are so many young and old self-starters who would not let age, language or educational background limit them.
It?s an environment where only the strong and the persistent will survive, where prejudice and discrimination take a backseat to ?making things happen?. If you have a dream you want made come true, and you are working on the Web, you?re in the right place.
After a one-week hiatus due to Disrupt (did you miss us?) we're back in the trusty TechCrunch TV studio with a brand new episode of CrunchWeek, the show where a few of us writers chat up the most interesting stories from the past seven days.
From party favor to plant protector, these cardboard tubes can take on <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-paper-towel-rolls_b_2239418.html">many different roles</a>.
5 Uses for Wrapping Paper
From drawer liners to photo backdrops, check out <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-wrapping-paper_b_2408899.html">other new uses</a> for wrapping paper.
5 Uses for Vodka
Explore these alternative ways <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-vodka_b_2324549.html">you can use vodka</a>.
5 Uses for Wine Corks
Take a look at these 5 different <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-wine-corks_b_2277640.html#slide=1873298">new uses for wine corks</a>.
5 Uses For Jeans
Before you toss them, check out these great <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-jeans_b_2193893.html">ways to repurpose them</a>.
5 Uses For Tires
Just because you can't <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-tires_b_2123875.html">use them on your car anymore</a> doesn't mean they're useless!
5 Uses For Bubble Wrap
From artwork to insulation, this <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-bubble-wrap_b_2089920.html">loud packing material</a> can be used in many different ways.
5 Uses For Chocolate
The most unique ways to use all that <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-chocolate_b_2039421.html">leftover Halloween candy</a>.
5 Uses For Pumpkins
This <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-pumpkins_b_2024065.html">quintessential fall fruit</a> can actually be used for more than just decor and pie.
5 Uses For Sand
A <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-sand_b_2005438.html?utm_hp_ref=huffpost-home&ir=HuffPost Home" target="_hplink">candle holder, spill cleaner and more</a>!
5 Uses For Rice
Not only is it a culinary staple, but it can also <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-rice_b_1971550.html">help you with some chores</a> around the house.
5 Uses For Golf Balls
Create wall art and even plug your sink--no driving range necessary for <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-golf-balls_b_1952116.html">these new uses</a>.
5 Uses For Potatoes
Who knew this veggie could be so multi-purposed? Learn <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-potatoes_b_1937330.html">how to use a potato</a> to create stamps, remove a lightbulb and more!
5 Uses For Maps
Make coasters, a purse and more <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-maps_b_1910138.html">all with maps</a>.
5 Uses For Keys
Ever wonder what to do with your old keys? Repurpose them in <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-keys_b_1893746.html">these 5 new ways</a>.
5 Uses For Dish Soap
Use dish soap to make an ice pack, wash your hair and more, with these <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-other-uses-dish-soap_b_1874310.html">5 new uses</a>.
5 Uses For Nail Polish Remover
Did you know this beauty product can not only <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-unusual-uses-nail-polish-remover_b_1854705.html">clean stains on china</a>, but also dissolve super glue!
5 Uses For Action Figures
They're not just for kids! Learn <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-action-figures_b_1775386.html">5 other things you can do with action figures</a>.
5 Uses For A Cooler
It's not just for chilling soda (or beer)! Check out the <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-uses-for-cooler_b_1819257.html">5 other uses for a cooler</a>.
5 Uses For Rubber Bands
Use this common office supply to grip a bottle, open a lid and more! Check out these <a href="http://www.huffingtonpost.com/chris-barnes/uses-for-rubber-bands_b_1775602.html">5 uses for rubber bands</a>.
5 Uses For Cards
You can do these <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-uses-for-cards_b_1752873.html">5 things with cards</a>... and not one of them involves gambling!
5 Uses For Duct Tape
Who knew that this material could be used to make a wallet? Learn how to use duct tape for <a href="http://www.huffingtonpost.com/chris-barnes/new-uses-for-duct-tape_b_1721986.html">this and four more things</a>.
5 Uses For Milk
It does wonders for your...hair? Check out the <a href="http://www.huffingtonpost.com/chris-barnes/uses-for-milk_b_1698762.html">ways you can use milk to clean and polish </a>things around your home.
5 Uses For Pill Bottles
Who knew that besides holding pills, <a href="http://www.huffingtonpost.com/chris-barnes/uses-for-pill-bottles_b_1679568.html">these containers could be used as a water resistant survival kit</a>? Now that's a reason to hold on to these!
5 Uses For Paper Clips
Learn how paperclips can help <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-paper-clips_b_1661794.html">you fix your electronics AND pit a cherry</a>.
5 Uses For Peroxide
Use peroxide to do anything from cleaning your cutting board to highlighting your hair. Read about <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-for-peroxide_b_1647151.html">those new uses and more</a>!
5 Uses For Eggshells
From removing stains to a great fertilizer, here are <a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-new-uses-eggshells_b_1627522.html">even more reasons to love eggs</a>!
5 Uses For Cornstarch
This vegetable-based powder <a href="http://www.huffingtonpost.com/chris-barnes/5-uses-for-cornstarch_b_1607654.html">works wonders removing grease</a> and cleaning your...pet!
5 Uses For Lemons
This fruit is more than just delicious--<a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-5-new-uses-for-lemons_b_1588632.html">it can also do wonders</a> in your kitchen.
5 Uses For Milk Jugs
Find out how to get a few more uses out of plastic gallon containers before tossing them in the recycle bin.
5 Uses For Aspirin
The cure for m<a href="http://www.huffingtonpost.com/chris-barnes/repurposing-ideas-uses-for-aspirin_b_1552945.html">ore than just that throbbing headache</a>.
5 Uses For Sugar
Sugar isn't just for your coffee... <a href="http://www.huffingtonpost.com/chris-barnes/uses-for-sugar_b_1536525.html">Use it to feed your flowers</a>, remove grass stains and more.
5 Uses For Plastic Bags
Got a ton of pastic bags from all your grocery shopping? <a href="http://www.huffingtonpost.com/chris-barnes/5-new-uses-plastic-bags_b_1517919.html">Put them to good use</a>!
5 Uses For Vegetable Oil
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Study adds to evidence that cigarettes are gateway to marijuanaPublic release date: 5-May-2013 [ | E-mail | Share ]
Contact: Susan Stevens Martin ssmartin@aap.org 847-434-7131 American Academy of Pediatrics
Researchers also find that college students who use both tobacco and cannabis smoke more cigarettes per month than users of tobacco only
WASHINGTON, DC Teen smokers who rationalize their use of cigarettes by saying, "At least, I'm not doing drugs," may not always be able to use that line.
New research to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana.
"Contrary to what we would expect, we also found that students who smoked both tobacco and marijuana were more likely to smoke more tobacco than those who smoked only tobacco," said study author Megan Moreno, MD, MSEd, MPH, FAAP, an investigator at Seattle Children's Research Institute and associate professor of pediatrics at the University of Washington.
Dr. Moreno and her colleagues randomly selected incoming college students from two universities one in the Northwest and one in the Midwest to participate in the longitudinal study. Students were interviewed prior to entering college and again at the end of their freshman year regarding their attitudes, intentions and experiences with substances.
Specifically, students were asked if they had used tobacco or marijuana ever in their lives and in the past 28 days. Researchers also assessed the quantity and frequency of marijuana and tobacco use in the past 28 days.
Results showed that prior to entering college, 33 percent of the 315 participants reported lifetime tobacco use, and 43 percent of lifetime users were current users. In addition, tobacco users were more likely to have used marijuana than those who did not use tobacco.
By the end of their freshman year, 66 percent of participants who reported tobacco use prior to entering college remained current users with an average of 34 tobacco episodes per month. Of these, 53 percent reported concurrent marijuana use. Overall, users of both substances averaged significantly more tobacco episodes per month than current users of tobacco only (42 vs. 24).
"These findings are significant because in the past year we have seen legislation passed that legalizes marijuana in two states," Dr. Moreno said. "While the impact of these laws on marijuana use is a critical issue, our findings suggest that we should also consider whether increased marijuana use will impact tobacco use among older adolescents."
Future work should involve designing educational campaigns highlighting the increased risks of using these substances together, Dr. Moreno concluded.
###
To schedule an interview with Dr. Moreno before or during the PAS meeting, contact Mary Guiden, public relations specialist at Seattle Children's Hospital, at 206-987-7334 or mary.guiden@seattlechildrens.org.
To view the abstract, "Trends in Tobacco and Marijuana Use among College Freshman," go to http://www.abstracts2view.com/pas/view.php?nu=PAS13L1_2195.5.
Funded by National Institutes of Health, the Common Fund, managed by the Office of Strategic Coordination, grant R01DA031580-03.
The Pediatric Academic Societies (PAS) are four individual pediatric organizations that co-sponsor the PAS Annual Meeting the American Pediatric Society, the Society for Pediatric Research, the Academic Pediatric Association, and the American Academy of Pediatrics. Members of these organizations are pediatricians and other health care providers who are practicing in the research, academic and clinical arenas. The four sponsoring organizations are leaders in the advancement of pediatric research and child advocacy within pediatrics, and all share a common mission of fostering the health and well-being of children worldwide. For more information, visit http://www.pas-meeting.org. Follow news of the PAS meeting on Twitter at http://twitter.com/PedAcadSoc.
[ | E-mail | Share ]
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Study adds to evidence that cigarettes are gateway to marijuanaPublic release date: 5-May-2013 [ | E-mail | Share ]
Contact: Susan Stevens Martin ssmartin@aap.org 847-434-7131 American Academy of Pediatrics
Researchers also find that college students who use both tobacco and cannabis smoke more cigarettes per month than users of tobacco only
WASHINGTON, DC Teen smokers who rationalize their use of cigarettes by saying, "At least, I'm not doing drugs," may not always be able to use that line.
New research to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana.
"Contrary to what we would expect, we also found that students who smoked both tobacco and marijuana were more likely to smoke more tobacco than those who smoked only tobacco," said study author Megan Moreno, MD, MSEd, MPH, FAAP, an investigator at Seattle Children's Research Institute and associate professor of pediatrics at the University of Washington.
Dr. Moreno and her colleagues randomly selected incoming college students from two universities one in the Northwest and one in the Midwest to participate in the longitudinal study. Students were interviewed prior to entering college and again at the end of their freshman year regarding their attitudes, intentions and experiences with substances.
Specifically, students were asked if they had used tobacco or marijuana ever in their lives and in the past 28 days. Researchers also assessed the quantity and frequency of marijuana and tobacco use in the past 28 days.
Results showed that prior to entering college, 33 percent of the 315 participants reported lifetime tobacco use, and 43 percent of lifetime users were current users. In addition, tobacco users were more likely to have used marijuana than those who did not use tobacco.
By the end of their freshman year, 66 percent of participants who reported tobacco use prior to entering college remained current users with an average of 34 tobacco episodes per month. Of these, 53 percent reported concurrent marijuana use. Overall, users of both substances averaged significantly more tobacco episodes per month than current users of tobacco only (42 vs. 24).
"These findings are significant because in the past year we have seen legislation passed that legalizes marijuana in two states," Dr. Moreno said. "While the impact of these laws on marijuana use is a critical issue, our findings suggest that we should also consider whether increased marijuana use will impact tobacco use among older adolescents."
Future work should involve designing educational campaigns highlighting the increased risks of using these substances together, Dr. Moreno concluded.
###
To schedule an interview with Dr. Moreno before or during the PAS meeting, contact Mary Guiden, public relations specialist at Seattle Children's Hospital, at 206-987-7334 or mary.guiden@seattlechildrens.org.
To view the abstract, "Trends in Tobacco and Marijuana Use among College Freshman," go to http://www.abstracts2view.com/pas/view.php?nu=PAS13L1_2195.5.
Funded by National Institutes of Health, the Common Fund, managed by the Office of Strategic Coordination, grant R01DA031580-03.
The Pediatric Academic Societies (PAS) are four individual pediatric organizations that co-sponsor the PAS Annual Meeting the American Pediatric Society, the Society for Pediatric Research, the Academic Pediatric Association, and the American Academy of Pediatrics. Members of these organizations are pediatricians and other health care providers who are practicing in the research, academic and clinical arenas. The four sponsoring organizations are leaders in the advancement of pediatric research and child advocacy within pediatrics, and all share a common mission of fostering the health and well-being of children worldwide. For more information, visit http://www.pas-meeting.org. Follow news of the PAS meeting on Twitter at http://twitter.com/PedAcadSoc.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Epilepsy cured in mice using brain cellsPublic release date: 5-May-2013 [ | E-mail | Share ]
Contact: Jeffrey Norris jeff.norris@ucsf.edu 415-502-6397 University of California - San Francisco
UC San Francisco cell therapy raises hope for severe human forms
UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated with seizures, as well as with learning and memory. Other researchers had previously used different cell types in rodent cell transplantation experiments and failed to stop seizures.
Cell therapy has become an active focus of epilepsy research, in part because current medications, even when effective, only control symptoms and not underlying causes of the disease, according to Scott C. Baraban, PhD, who holds the William K. Bowes Jr. Endowed Chair in Neuroscience Research at UCSF and led the new study. In many types of epilepsy, he said, current drugs have no therapeutic value at all.
"Our results are an encouraging step toward using inhibitory neurons for cell transplantation in adults with severe forms of epilepsy," Baraban said. "This procedure offers the possibility of controlling seizures and rescuing cognitive deficits in these patients."
The findings, which are the first ever to report stopping seizures in mouse models of adult human epilepsy, will be published online May 5 in the journal Nature Neuroscience.
During epileptic seizures, extreme muscle contractions and, often, a loss of consciousness can cause seizure sufferers to lose control, fall and sometimes be seriously injured. The unseen malfunction behind these effects is the abnormal firing of many excitatory nerve cells in the brain at the same time.
In the UCSF study, the transplanted inhibitory cells quenched this synchronous, nerve-signaling firestorm, eliminating seizures in half of the treated mice and dramatically reducing the number of spontaneous seizures in the rest. Robert Hunt, PhD, a postdoctoral fellow in the Baraban lab, guided many of the key experiments.
In another encouraging step, UCSF researchers reported May 2 that they found a way to reliably generate human MGE-like cells in the laboratory, and that, when transplanted into healthy mice,the cells similarly spun off functional inhibitory nerve cells. That research can be found online in the journal Cell Stem Cell.
In many forms of epilepsy, loss or malfunction of inhibitory nerve cells within the hippocampus plays a critical role. MGE cells are progenitor cells that form early within the embryo and are capable of generating mature inhibitory nerve cells called interneurons. In the Baraban-led UCSF study, the transplanted MGE cells from mouse embryos migrated and generated interneurons, in effect replacing the cells that fail in epilepsy. The new cells integrated into existing neural circuits in the mice, the researchers found.
"These cells migrate widely and integrate into the adult brain as new inhibitory neurons," Baraban said. "This is the first report in a mouse model of adult epilepsy in which mice that already were having seizures stopped having seizures after treatment."
The mouse model of disease that Baraban's lab team worked with is meant to resemble a severe and typically drug-resistant form of human epilepsy called mesial temporal lobe epilepsy, in which seizures are thought to arise in the hippocampus. In contrast to transplants into the hippocampus, transplants into the amygdala, a brain region involved in memory and emotion, failed to halt seizure activity in this same mouse model, the researcher found.
Temporal lobe epilepsy often develops in adolescence, in some cases long after a seizure episode triggered during early childhood by a high fever. A similar condition in mice can be induced with a chemical exposure, and in addition to seizures, this mouse model shares other pathological features with the human condition, such as loss of cells in the hippocampus, behavioral alterations and impaired problem solving.
In the Nature Neuroscience study, in addition to having fewer seizures, treated mice became less abnormally agitated, less hyperactive, and performed better in water-maze tests.
###
Additional UCSF study authors include Arturo Alvarez-Buylla, PhD, UCSF professor of neurological surgery; John Rubenstein, MD, PhD, UCSF professor of psychiatry; and Kelly Girskis, staff research associate. The research was funded by the National Institutes of Health and by the California Institute of Regenerative Medicine.
UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Epilepsy cured in mice using brain cellsPublic release date: 5-May-2013 [ | E-mail | Share ]
Contact: Jeffrey Norris jeff.norris@ucsf.edu 415-502-6397 University of California - San Francisco
UC San Francisco cell therapy raises hope for severe human forms
UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated with seizures, as well as with learning and memory. Other researchers had previously used different cell types in rodent cell transplantation experiments and failed to stop seizures.
Cell therapy has become an active focus of epilepsy research, in part because current medications, even when effective, only control symptoms and not underlying causes of the disease, according to Scott C. Baraban, PhD, who holds the William K. Bowes Jr. Endowed Chair in Neuroscience Research at UCSF and led the new study. In many types of epilepsy, he said, current drugs have no therapeutic value at all.
"Our results are an encouraging step toward using inhibitory neurons for cell transplantation in adults with severe forms of epilepsy," Baraban said. "This procedure offers the possibility of controlling seizures and rescuing cognitive deficits in these patients."
The findings, which are the first ever to report stopping seizures in mouse models of adult human epilepsy, will be published online May 5 in the journal Nature Neuroscience.
During epileptic seizures, extreme muscle contractions and, often, a loss of consciousness can cause seizure sufferers to lose control, fall and sometimes be seriously injured. The unseen malfunction behind these effects is the abnormal firing of many excitatory nerve cells in the brain at the same time.
In the UCSF study, the transplanted inhibitory cells quenched this synchronous, nerve-signaling firestorm, eliminating seizures in half of the treated mice and dramatically reducing the number of spontaneous seizures in the rest. Robert Hunt, PhD, a postdoctoral fellow in the Baraban lab, guided many of the key experiments.
In another encouraging step, UCSF researchers reported May 2 that they found a way to reliably generate human MGE-like cells in the laboratory, and that, when transplanted into healthy mice,the cells similarly spun off functional inhibitory nerve cells. That research can be found online in the journal Cell Stem Cell.
In many forms of epilepsy, loss or malfunction of inhibitory nerve cells within the hippocampus plays a critical role. MGE cells are progenitor cells that form early within the embryo and are capable of generating mature inhibitory nerve cells called interneurons. In the Baraban-led UCSF study, the transplanted MGE cells from mouse embryos migrated and generated interneurons, in effect replacing the cells that fail in epilepsy. The new cells integrated into existing neural circuits in the mice, the researchers found.
"These cells migrate widely and integrate into the adult brain as new inhibitory neurons," Baraban said. "This is the first report in a mouse model of adult epilepsy in which mice that already were having seizures stopped having seizures after treatment."
The mouse model of disease that Baraban's lab team worked with is meant to resemble a severe and typically drug-resistant form of human epilepsy called mesial temporal lobe epilepsy, in which seizures are thought to arise in the hippocampus. In contrast to transplants into the hippocampus, transplants into the amygdala, a brain region involved in memory and emotion, failed to halt seizure activity in this same mouse model, the researcher found.
Temporal lobe epilepsy often develops in adolescence, in some cases long after a seizure episode triggered during early childhood by a high fever. A similar condition in mice can be induced with a chemical exposure, and in addition to seizures, this mouse model shares other pathological features with the human condition, such as loss of cells in the hippocampus, behavioral alterations and impaired problem solving.
In the Nature Neuroscience study, in addition to having fewer seizures, treated mice became less abnormally agitated, less hyperactive, and performed better in water-maze tests.
###
Additional UCSF study authors include Arturo Alvarez-Buylla, PhD, UCSF professor of neurological surgery; John Rubenstein, MD, PhD, UCSF professor of psychiatry; and Kelly Girskis, staff research associate. The research was funded by the National Institutes of Health and by the California Institute of Regenerative Medicine.
UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care.
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.